ABSTRACT
Introduction: Molluscum contagiosum (MC) is a common skin and mucosal disease caused by MC virus of pox virus family. Lesion manifests both in immunocompromised and immunocompetent individuals. Case Presentation: The case is of MC in 40 year old female patient on right cheek since three months. The growth was asymp- tomatic and nodular. HIV status of the patient was negative with no other medical history. The excised specimen on histological examinations showed lobules of proliferating epithelium. Cells in the center showed basophilic viral inclusion bodies called “Henderson-Paterson bodies” based on these features lesion was diagnosed as MC. Management and prognosis: Lesion was treated surgically. Follow up of six months showed no recurrence or any new lesions. Conclusion: MC is commonly manifested in immunocompromised patients but can rarely be present in immunocompetent patient, so should be considered in the list of differential diagnosis.